Jack Ross has made six changes to the side that lost on Saturday with debuts for Darryl Duffy and Liam Smith.
Out go Craig Samson, Gary Irvine, Stelios Demetriou, Gary MacKenzie, John Sutton and Gavin Reilly to be replaced by Ross Stewart, Smith, Adam Eckersley, Gregor Buchanan, Ross Stewart and Duffy.
MacKenzie is rested ahead of Saturday's match against Livingston with the other five players dropping to the bench.
Adam Eckersley comes in for his first appearance of the season after suffering an injury during pre-season training.
Kick-off is at 7:45pm and we'll have all the action covered on our Facebook and Twitter pages. Supporters outside the UK and Ireland can watch tonight's match on St Mirren TV.
St Mirren: Stewart, L. Smith, Baird, Buchanan, Eckersley, Morgan, McShane, McGinn, C.Smith, Stewart, Duffy
Subs: Samson, Stelios, Irvine, Kirkpatrick, O'Keefe, Reilly, Sutton