Jack Ross makes two changes from the side that lost to Dunfermline in the Ladbrokes Championship.
Gary MacKenzie returns from injury in place for Jack Baird, while David Clarkson drops out to be replaced by Lawrence Shankland.
Rocco Quinn is on the bench after a spell out injured and there's also a place amongst the substitutes for Development Squad striker Kalvin Orsi who has impressed the manager in training.
Kick off is at 8pm as the Saints look to progress to the fourth round of the Scottish Cup and set up a meeting with Premiership side Dundee.
St Mirren XI: Gallacher, Naismith, Gordon, MacKenzie, Irvine, McAllister, Mallan, Magennis, Morgan, Sutton, Shankland
St Mirren Subs: Langfield, Baird, Quinn, McLear, Gallagher, Clarkson, Orsi